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Whilst there's a lot to enjoy in A Wrinkle in Time, its poor plotting means that it comes across as confused overall.
The film is very well intentioned: it has a beautiful message about loving yourself and all of the actors do a fantastic job of bringing that message to life. Another commendable aspect is the visual effects, although on a technical level the camera angles could've shown off the great effects in more detail.
Unfortunately, it also fails at balancing both Science Fiction and Fantasy, as it makes missteps on paths which are crucial to both genres. The story is first set up to be sceince based, but they only explain the science of the plot very briefly, making much of the later story hard to swallow as the audience lacks understanding of how this is all happening in the first place. Similarly, Fantasy only really works when you set it in a world with its own rules and they make little to no effort to explain the inner workings of the films' universe, again meaning that later events lack impact, simply due to a lack of understanding from the audience. The exposition-heavy dialogue towards the beginning of the film also comes across as clunky, which really doesn't help.
Overall, A Wrinkle in Time has good enough acting, visuals and story to be entertaining and it has a beautiful message at its core, but the lack of attention to detail in the script make it far from perfect.